Thursday, November 14, 2019
The Necklace by Guy de Maupassant Essay -- Guy Maupassant Necklace Ess
The Necklace by Guy de Maupassant ?The Necklace? The theme of Guy de Maupassant story ?The Necklace? seems to be suggested by the line, ?What would have happened if Mathilde had not lost the necklace. Mathilde Loisel grew up in poverty and had no expectations in life. When she got married, her and her husband would sit around the dinner table and imagine they were eating a luxurious meal. They would imagine using shiny silverware and eating their meal on marvelous plates. Together, they had nothing. Mathilde had no clothes, no jewels, and only one friend. One day her husband came home from work and handed her an invitation they had received to attend a ball. Her husband thought that she would be enthusiastic about it, however she busted out in tears. She wanted to attend, yet she had no dress to wear. After digging in to money they had been trying to saved, Mathilde purchased a dress for the ball. As the ball drew near, Mathilde decided she still needed something more to finish off the dress they had just spent ...
Tuesday, November 12, 2019
Infant Motor Developm
Infant Motor DevelopmentI.  First MonthA.   can already raise its head for a momentB.    twists its head from side to side when lying on rearC.    hands remain grittedD.   has already a sturdy clutch reflexE.    stares and goes after object moving ahead of him/her (range of 45 degrees)F.     performs husky soundsG.   gazes closely at parents when they speak to him/herII.               Second MonthA.   raises its head about 45 degrees when resting on stomachB.    head nods forward when grasp in sitting positionC.    clutch reflex declinesD.   goes after hanging objects with eyesE.    makes smilesIII.            Third MonthA.   begins to stand partial load on both legs when clutched in a standing positionB.    able to grasp head up when sitting but still nods frontwardC.    can lift head and shoulders when resting on stomach (amid 45 and 90 degrees)D.   stands load on forearmsE.    grasps objects but does not get in touch with themF.     grasps own hands and drags at bedspreads and clothesG.   goes after object (180 degrees)H.   makes more soundsI.      smiles when sees recognizable features.IV. Fourth MonthA.   has already a fine head controlB.    sits with helpC.    stands some load on legs when clutched erectD.   lifts head and chest off plane (90 degree angle)E.    turns from back to sideF.     discovers and plays with handsG.   attempts to get in touch with but missesH.   clutches objects with two handsV.  Fifth MonthA.  sign of teething startsB.  grasps head up when sittingC.  turns from abdomen to rearD.  p laces feet to mouth when resting on rearE.   freely holds objects and gets objects openly to mouthVI. Sixth MonthA.   starts to masticate and nibbleB.    raises head when dragged to a sitting positionC.    turns form rear to abdomenD.   holds and manages small objectsE.    clutches bottleF.     seizes feet and drags to mouthG.   bends body to make out an objectH.   twists head from side to side and then stares up or downVII. Seventh MonthA.  learns to sit without help (may bend forwards on two hands)B.  stands full load on feetC.  springs when grasped in standing positionD.  shifts objects from one hand to anotherE.  hits objects on planesF.   and able to grip on small objectsVIII.   Eight MonthA.  sits fine without helpB.   stands load on legs and may rest holding on to fixturesC.   lifts out up objects by index, fourth, and fifth fi nger alongside thumbD.   able to discharge objectsE.   drags cords to get objectsF.   seeks for objects that are farIX.  Ninth MonthA.   starts swarmingB.    drags up to standing position from sittingC.   sits for extended time (at most 10 minutes)D.  employs thumb and index finger to lift up objectsE.   places arms ahead of face to shun having it washedX.  Tenth MonthA.  goes from abdomen to sitting positionB.  sits by rundownC.  recuperates balance effortlessly while sittingD.  raises one foot to make a step while standingE.   wields byeF.   recurs actions that draw attentionXI.  Eleventh MonthA.   learns to stroll gripping on to fixtures or other objectsB.    puts one object following another into a potC.    returns back to lift up an object while sittingD.   able to control objects out of stretched fitting placesE.    turns a ball when requested, and quakes head for rebuffXII.  Twelfth MonthA.   strolls with one hand graspB.    bears and tries first steps unaidedC.    rests from standing position aloneD.   tries to construct two chunk towers but may fall shortE.    goes after fast moving objectsF.     grips to parents in odd circumstancesG.   seeks object where it was previously seenReferences:Piek, J. P. (2006). Infant Motor Development. Human Kinetics Publishers.Gallahue, D. L. (2006). Understanding Motor Development: Infants, Children, Adolescents,      Adults. McGraw-Hill Companies.
Sunday, November 10, 2019
Terrorism Case Study
Caless (2012) defines terrorism as †the threat or use of violence to further a political agenda for change by inducing widespread fear†. However, experts have been debating over a clear definition for terrorism for over 100 years. Although the word was first used over 200 years ago when discussing the Reign of Terror (Whitaker, 2001). Consequently, there have been over 100 definitions offered for terrorism (Laqueur, 1977, cited in Martin, 2013). Alex Schmid's (2004) research also illustrates the lack of clarity surrounding the definition.And most experts believe that an impartial and universal recognised definition will never be agreed upon (Ganor, 2002). With the lack of clarity surrounding the definition, a further question arises; who is classed as a terrorist? This is reflected in the well known phrase â€Å"one man's freedom fighter, is another man's terrorist. †(Gerald Seymour, 1975, cited in Ganor, 2002). Overall, it is agreed, that this depends on the sub jective viewpoint of the individual (Ganor, 2002; Jackson, 2008; Corte, 2007).The Just War doctrine is an â€Å"ideal and moralistic philosophy†(Martin, 2013). It asks questions such as â€Å"what types of force are morally acceptable? †and â€Å"who can morally be defined as an enemy? †This notion is usually used by ideological and religious extremists, in order to justify their own acts of extreme violence. A prime example of religious extremists is the ‘jihadi Islamic fundamentalists', the term jihad means a sacred â€Å"struggle†but is manifested by some radical Muslim clerics as a holy war and therefore perceived that their war is a â€Å"just war†(Martin, 2013).This paper will endeavour to answer the question; Did University College London (UCL) further radicalise Umar Farouk Abdulmutallab? There have been many debates, theories and investigations surrounding this question, many of which will be analysed throughout. Umar Farouk Abd ulmutallab (born 22 December 1986) is a Nigerian Islamist who attempted to detonate plastic explosives in his underwear whilst travelling from Amsterdam to Detroit, on Christmas Day 2009, on the Northwest Airlines Flight 253. In January 2005 Abdulmutallab joined an Islamic forum under the pseudonym â€Å"Farouk1986†(Now Public, 2009).He frequently contributed to the forum. His postings normally gave advice to other forum members, although on occasion he expressed more personal views. These included his â€Å"jihad fantasies†, describing how â€Å"Muslims will win and rule the world†and prays to Allah to â€Å"unite us all Muslims and give us victory over those who do not believe†. The majority of his postings illustrate his loneliness and his struggle to contain his â€Å"sexual drive†, and he goes on to urge fellow forum users to limit their activities to â€Å"Islamically good†and to only â€Å"hang around with good Muslims who enjoy s tudying†.Throughout his postings in the forum he maintains that he is memorising the Quran (Islamic Forum, 2005). These postings illustrate that Abdulmutallab's views on the Islamic religion, are very similar to Salafism or Olivier Roy's neo-fundamentalism (see: Social Science Research Council). This is shown with his fixation on personal faith, and is also portrayed when he praises Shaykhs Saud as-Shuraim and Abdul Rahman as Sudais (Islamic Forum, 2005). Another radical Muslim he mentions is Abdullah el-Faisal, who is currently in prison in the UK for influencing his supporters to murder Jews, Hindus and Americans (Forest, 2012).Some of the media (Gardham, 2009) focused on Abdulmutallab's love for football and this is clearly seen within his postings online. However, by November 15th 2005, he had turned against it stating â€Å"Let’s save our honor and religion and try to stay away from football and do sporting activities that are more Islamically beneficial†¦ ru nning, paintball, archery (or any other sport of the like that teaches [how to] target and aim). †(Islamic Forum, 2005). There are many different theories as to where Abdulmutallab was further radicalised, the one that will be discussed in this paper is the possibility hat University College London (UCL) and it's Islamic Society were the perpetrators. During the investigation of the attempted attack of Flight 253, the University College of London (UCL) had held their own investigation of their Islamic Society and although the evidence holds strongly against them, as will be seen throughout this paper, they came to their own conclusion that  there was â€Å"no evidence to suggest either that Umar Farouk Abdulmutallab was radicalised while a student at UCL, or that conditions at UCL during that time or subsequently were conducive to the radicalisation of students. (UCL, 2010). Umar Farouk Abdulmutallab began university, in September 2005, during a peak of Islamist activity in the UK, there were events organised by Ikhwan (Ikhwan Web, 2005) and Jamaat-e-Islami inspired groups that were being held weekly and their influence over British Islam was steadily increasing (Hitchens, 2010). This year is an important one, as the emergence of the first Islamic militant groups in Bangladesh (Kabir, 2005) were seen and Islam became the official religion of Iraq (Islamopedia Online).British Islamists were exploiting the wars in Afghanistan and Iraq and implicating the Western governments with the â€Å"war on Islam and Muslims,†(Hitchens, 2010). According to Islamist's, Western Muslims, had a duty to stand up for their religion and fight back using peaceful methods (O'Connor, 2012). The â€Å"Stop Police Terror†lecture was given by Awlaki at the East London Mosque in 2003 (YouTube, 2011). The listed supporters of this group could be found on the Stop Political Terror website, and interestingly UCL was among this list (Stop Political Terror, 2003- 2005).The aims of this campaign was to urge Muslims to fight against the â€Å"anti-terrorist police†and to alert them of â€Å"the deteriorating situation in the UK and the scale of arrests, raids and abuse meted out [against Muslims] by Anti-Terrorist Police. †The campaign statement also included a clear warning: â€Å"Britain's Muslims, as a community, will refuse to cooperate with the law enforcement authorities if this abuse continues. †(Stop Political Terror, 2003-2005). During this time, the Federation of Student Islamic Societies (FOSIS) ran another campaign alongside â€Å"Stop Political Terror. , issuing further explicit statements -â€Å"previously, it was Muslims themselves under attack, now the agenda [is] to attack Islam, its principles †¦ New laws making it an offence †¦ aim to divide and weaken the Muslim community. †And â€Å"The relative concept of ‘extremism’ is being used to condemn Muslims from very diverse political viewpoints. †(Hitchens, 2010). The perception of a Western â€Å"war on Islam†is one of the key recruitment tools of global jihadist groups like al-Qaeda (Home Office, 2011).Therefore, it is clear that Abdulmutallab was absorbed in an protesting setting, and this appeared to him to give value and objective, to his already pre-existing neo-fundamentalist attitude and personal discontent (loneliness). It is also apparent from his previous online statements, that he was vulnerable to the indoctrination; â€Å"I hope to get over my loneliness when I go to university†¦ where there are usually Islamic groups [and] clubs with good Muslims†(Islamic Forum, 2005).His obsession with Islam is clearly illustrated with the amount of time he devoted to the group, and after a year of starting university he was already president of UCL's Islamic Society (Irvine, 2009). Terrorist groups are also known to use the media to their advantage. As terrorism is à ¢â‚¬Å"not limited to specific locales or regions†and the media has allowed everybody to witness some form of terror. Knowing this terrorist groups can therefore understand the power of the images and manipulate them to their advantage (Martin, 2013).Gus Martin (2013) explains the media frenzy surrounding terrorism, and describes the 21st century as being â€Å"an era of globalized terrorism†. Another key recruitment tool that jihad groups use is the internet (US Department of Defense, 2007). Sites such as Facebook, (Torok, 2011) and the creation of websites that can be regionalised. Although governments monitor the websites and, if necessary shut them down, another website can be made and the process can start again (McNeal, 2008). It is clear that Abdulmutallab was a fan of internet use, with his frequent postings on the Islamic Forum.Awlaki could also be an key element in the â€Å"jihad internet recruitment†process. The media present him as the â€Å"Bin La den of the internet†(Madhani 2010; CNN, 2011). He was a Muslim lecturer and spiritual leader who had been accused of being a senior al-Qaeda â€Å"effective global recruiter†(Telegraph, 2012) and motivator. He is thought to have given a series of video link lectures at the East London Mosque (Gilligan, 2010). They however, categorically deny this ever took place, and deny that Abdulmutallab even attended the Mosque (East London Mosque, 2010). The University of Westminster Islamic Society are alleged to have ties with Awlaki.Another Islamic Forum announced him as a guest at University of Westminster Islamic Society Annual Dinner in 2006 (Ummah Forum, 2006). Along with these connections Awlaki is also suspected to have had â€Å"recruited†Abdulmutallab before the attack. According to Fox News, an FBI bulletin states that Awlaki showed Abdulmutallab â€Å"how to detonate the bomb†(Catherine Herridge, 2011). Research carried out by the University of Cam bridge suggest that â€Å"the majority of young British Muslims are opposed to political Islam, and are more likely to join Amnesty International†(Cambridge University, 2008).This was criticised, when Anthony Glees accused Cambridge of trying to prove that British universities are not â€Å"hotbeds of Islamic radicalism†and called the research â€Å"flimsy and uncompelling†(Lipsett, 2008). Their research was argued against by the Centre for Social Cohesion (CSC), who stated that â€Å"Umar Farouk Abdulmutallab was radicalised at University College London†, and goes on to describe British universities as the â€Å"breeding grounds of Islamic extremism†(Centre for Social Cohesion, 2010).They describe themselves as the â€Å"Centre [that] has been at the forefront of the debate on what role Universities should play in ensuring that British students do not fall victim to the ideology of violent Islamism. †(Centre for Social Cohesion, 2010). They went on to completely contradict Cambridge Universities report, and suggested within the report that Islamic extremism will â€Å"flourish†. This statement was further supported when Abdulmutallab became the fifth president of a UK Islamic society to face terrorist charges (Weiss, 2011).The vulnerability of Abdulmutallab along with the recruitment tools of jihadist groups illustrate how easily individuals can slip beyond this porous boundary rapidly and very often unnoticed. Since the September 11th attack on the World Trade Center, it has become apparent that Al-Qaeda are focusing on mobilising Western Muslims to commit â€Å"lone-wolf†terror (RUSI, 2012). This evidence is supported by the ICSR (2011) who describe Awlaki's role as â€Å"ideological rather than operational†and explain that the greatest threat he poses is the mobilisation of Western Muslims through his sermons and therefore expanding the jihadi movement.Umar Farouk Abdulmutallab's extremis t views are apparent very early on. Although, as his loneliness grew, so did his radical views. It appears that he was trying to fight his urges to act upon these views time after time. Abdulmutallab was quite clearly an â€Å"extremist†turned â€Å"terrorist†, as it is clearly defined by Martin (2013); â€Å"extremists†who violently act out their extremist beliefs are â€Å"terrorists†. It is clear that his time at UCL and within the Islamic Society unquestionably played a part in Abdulmutallab's further radicalisation when examining the evidence discussed.It is also remarkable to see that UCL was among the list of supporters of the Stop Police Terror campaigns, almost condemning themselves of the radicalisation. They contradicted themselves when they released their findings that â€Å"no evidence to suggest †¦ that conditions at UCL †¦ [are] conducive to the radicalisation of students. †(UCL, 2010). It is noted that Cambridge Univers ity's ‘flimsy' research could support the UCL's outcome, but then could this research, with their ‘bad press', also diminish their findings.Overall, there are many factors that led to the radicalisation of Abdulmutallab, his state of mind, his vulnerability, and the people that he was associated with within the Islamic Society. Therefore, the UCL was not completely at fault, it was also the fundamentalists, that infiltrated the system and took advantage of a vulnerable, young Muslim. References Caless, B (2012) ‘Terrorism and Political Violence: Introduction, Overview and the Problem with Definitions. (Accessed: 5 December 2012). Cambridge University (2008) ‘Campus radicalism fears too extreme? ‘ Available at: http://www. cam. ac. k/research/news/campus-radicalism-fears-too-extreme/ (Accessed: 5 December 2012). CNN Online (2011) ‘ Al-Awlaki: Who was he? ‘, CNN Online, Available at: http://security. blogs. cnn. com/2011/09/30/al-awlaki-who-wa s-he/ (Accessed: 5 December, 2012). De La Corte, L (2007) ‘Explaining Terrorism: A Psychosocial Approach' Perspectives on Terrorism, North America, Vol. No. 2 [Online] Available at: . (Accessed: 5 Dec. 2012). East London Mosque (2010) ‘ East London Mosque and London Muslim Centre  Statement on Anwar Awlaki' [Online] Available at: http://www. astlondonmosque. org. uk/uploadedImage/pdf/2010_11_07_15_44_46_Awlaki%20Statement%206%20Nov10%20-%20Full%20Statement. pdf (Accessed: 5 December, 2012) East London Mosque (2010) ‘ Sunday Mirror publish ELM letter' [Online] Available at: http://www. eastlondonmosque. org. uk/archive/news/243 (Acccessed: 5 December, 2012). Forest, J (2012) ‘Perception Challenges Faced by Al-Qaeda on the Battlefield of Influence Warfare. ‘ Perspectives on Terrorism, North America, Vol. 6, No. 2. [Online] Available at: . (Accessed: 05 Dec. 2012). Ganor, B. (2002) ‘Defining Terrorism- Is One Man's Terrorist Another Man' s Freedom Fighter? ‘. International Institute for Counter-Terrorism [Online]. Available at: http://www. ict. org. il/ResearchPublications/tabid/64/Articlsid/432/Default. aspx#Defining_Terrorism:_The_Present_Situation (Accessed: 1 December 2012). Gardham, D. (2009) ‘ Detroit bomber: internet forum traces journey from lonely schoolboy to Islamic fundamentalist', The Telegraph, 30 December 2009 [Online]. Available at: http://www. telegraph. o. uk/news/worldnews/northamerica/usa/6910776/Detroit-bo mber-internet-forum-traces-journey-from-lonely-schoolboy-to-Islamic-fundamentalist. html. (Accessed: 5 December 2012). Gilligan, A (2010) â€Å"East London Mosque: the terrorist question and the lies†, The Telegraph, 2 November 2010 [Online]. Available at: http://blogs. telegraph. co. uk/news/andrewgilligan/100061920/east-london-mosque-the-terrorist-connection-and-the-lies/ (Accessed: 5 December 2012). Gregory S. McNeal (2008). â€Å"Cyber Embargo: Countering the Internet J ihad† , Case Western Reserve Journal of International Law, vol. 9, pp. 789-826. [Online] Available at: http://works. bepress. com/gregorymcneal/15 (Accessed 1 December 2012) Herridge, C (2011). ‘ Awlaki Trained Suspected Christmas Jet Bomber How to Detonate Underwear, Document Reveals'. Fox News, 4 October 2011 [Online] Available at: http://www. foxnews. com/us/2011/10/04/al-awlaki-trained-suspected-christmas-day-jet-bomber-how-to-detonate-underwear/#ixzz2ECpGaSXS (Accessed:5 December 2012). Hitchens, A (2010) ‘The Making of the Christmas Day Bomber', Current Trends in Islamist Ideology, Vol. 10 [Online]. Available at: http://currenttrends. rg/research/detail/the-making-of-the-christmas-day-bomber (Accesed: 29 November 2012). Home Office (2011) Contest: The United Kingdom’s Strategy for Countering terrorism. London: The Stationery Office. (Cm. 8123). [Online] Available at: http://www. homeoffice. gov. uk/publications/counter-terrorism/counter-terrorism -strategy/strategy-contest? view=Binary (Accessed: 2 December 2012). ICSR (The International Centre for the Study of Radicalisation)(2011) ‘ICSR Insight: How Anwar al-Awlaki Became the Face of Western Jihad'. [Online] Available at: http://icsr. nfo/2011/09/icsr-insight-how-anwar-al-awlaki-became-the-face-of-western-jihad/ (Accessed: 5 December, 2012). Irvine, C (2009) ‘ Detroit terror attack: suspect president of university Islamic society', The Telegraph, 29 December 2009 [Online]. Available at: http://www. telegraph. co. uk/news/uknews/terrorism-in-the-uk/6902785/Detroit-terror-attack-suspect-president-of-university-Islamic-society. html (Accessed: 5 December, 2012) Ikhwan Web (2005) International Religious Freedom Report 2005. Available at: http://www. ikhwanweb. com/article. php? id=13543&ref=search. php
Friday, November 8, 2019
Using A After Certain Verbs Before Infinitives
Using 'A' After Certain Verbs Before Infinitives Having trouble explaining the a in the following sentence?  ¿Quieres aprender a jugar baloncesto? Would it be the same explanation as the personal a or is it just like the English to play basketball? Or neither of these? 'A' After a Verb Before Infinitives There very well may be an explanation here, but Im not sure what it is other than thats the way it is. There are certain verbs, and aprender is one of them, that need to be followed by a when followed by an infinitive. Why Spanish would use aspirbamos a nadar (with an a) for we aspired to swim but querà amos nadar (no a) for we wanted to swim appears arbitrary. There appear to be no clear rules to indicate when a verb needs to have an a before a subsequent infinitive, although verbs that indicate some sort of motion - such as venir (to come) and llegar (to leave) - usually do. So do some verbs that indicate a change in action, such as empezar (to begin). Following are the most common verbs that should be followed by a before an infinitive. Note that many of the verbs listed have more than one meaning; the meaning given is one that is often intended when the verb is followed by a and an infinitive: Acceder (to agree to): Los empresarios accedieron a estudiar las demandas de salario. The employers agreed to study the salary demands. Acercarse (to approach): Josà © se acercà ³ a ver si yo estaba bien. Jose approached in order to see if I was OK. Acostumbrarse (to be used to): No me acostumbro a perder. Im not used to losing. Alcanzar (to manage to): No alcanzaba a comprenderlo. I wasnt able to understand it. Aprender (to learn): Los hackers aprenden a camuflar el cà ³digo de sus ataques. Hackers are learning to camouflage their attack coding. Apresurarse (to hurry): Me apresurà © a leer algunos de los volà ºmenes de la serie. I hurried to read some volumes in the series. Aspirar (to aspire): Carlos aspiraba a ser senador. Carlos aspired to be a senator. Bajarse (to get down, lower oneself): Todos se bajaron a observar el fenà ³meno. Everyone got down to see the phenomenon. Comenzar (to begin): Comienzas a pensar. Youre beginning to think. Comprometerse (to promise): Se comprometieron a bajar los precios. They promised to lower prices. Decidirse (to decide): Me decidà a comprarlo. I decided to buy it. Dedicarse (to devote oneself): me dedico a hacer otro tipo de humor. I am dedicating myself to do another type of humor. Detenerse (to stop): Por eso me detuve a leerlo. Thats why I stopped to read it. Echar (to begin): Cuando salieron se echaron a correr. When they left they began to run. Empezar (to begin):  ¿Cundo empezarà © a sentirme mejor? When will I begin to feel better? Inclinarse (to be inclined): Me inclino a leer lo mejor de la literatura de autoayuda. I am inclined to read the best of the self-help literature. Ir (to go):  ¿Quieres saber cà ³mo vas a morir? Do you want to know how youre going to die? Llegar (to arrive, to succeed): Llegaremos a tener à ©xito. We will arrive at having success. Negarse (to refuse): Al principio se negà ³ a dar su nombre. At first, he refused to give his name. Parar (to stop): Pararon a comprar tortillas. They stopped to buy tortillas. Pasar (to come in): Pasaron a hablar con à ©l. They came in to talk with him. Ponerse (to start): Se puso a hablar en tercera persona. He began to talk in the third person. Quedarse (to remain): Nos quedamos a vivir con mi pap. We stayed to live with my father. Resignarse (to resign oneself): Me resignà © a ser và ctima. I resigned myself to being a victim. Resistirse (to resist): Se resistià ³ a ser detenido. He resisted being arrested. Romper (to suddenly begin): La pobre mujer rompià ³ a llorar. The poor woman broke out crying. Sentarse (to sit down): Nos sentamos a platicar sobre cualquier cosa. We sat down to chat about all sorts of things. Tender (to tend to):  ¿Por que las mujeres siempre tienden a enamorarse tan rpido? Why do women always tend to fall in love so fast? Venir (to come): Vinieron a ganar dinero. They came to earn money. Volver (to do again): No volverà © a ser joven. Im not going to be young again.
Tuesday, November 5, 2019
Enzyme Biochemistry - What They Are and How They Work
Enzyme Biochemistry - What They Are and How They Work An enzyme is defined as a macromolecule that catalyzes a biochemical reaction. In this type of chemical reaction, the starting molecules are called substrates. The enzyme interacts with a substrate, converting it into a new product. Most enzymes are named by combining the name of the substrate with the -ase suffix (e.g., protease, urease). Nearly all metabolic reactions inside the body rely on enzymes in order to make the reactions proceed quickly enough to be useful. Chemicals called activators can enhance enzyme activity, while inhibitors decrease enzyme activity. The study of enzymes is termed enzymology. There are six broad categories used to classify enzymes: Oxidoreductases - involved in electron transferHydrolases - cleave the substrate by hydrolysis (uptaking a water molecule)Isomerases - transfer a group in a molecule to form an isomerLigases (or synthetases) - couple the breakdown of a pyrophosphate bond in a nucleotide to the formation of new chemical bondsOxidoreductases - act in electron transferTransferases - transfer a chemical group from one molecule to another How Enzymes Work Enzymes work by lowering the activation energy needed to make a chemical reaction occur. Like other catalysts, enzymes change the equilibrium of a reaction, but they arent consumed in the process. While most catalysts can act on a number of different types of reactions, a key feature of an enzyme is that it is specific. In other words, an enzyme that catalyzes one reaction wont have any effect on a different reaction. Most enzymes are globular proteins that are much larger than the substrate with which they interact. They range in size from 62 amino acids to more than 2,500 amino acid residues, but only a portion of their structure is involved in catalysis. The enzyme has what is called an active site, which contains one or more binding sites that orient the substrate in the correct configuration, and also a catalytic site, which is the part of the molecule that lowers activation energy. The remainder of an enzymes structure acts primarily to present the active site to the substrate in the best way. There may also be allosteric site, where an activator or inhibitor can bind to cause a conformation change that affects the enzyme activity. Some enzymes require an additional chemical, called a cofactor, for catalysis to occur. The cofactor could be a metal ion or an organic molecule, such as a vitamin. Cofactors may bind loosely or tightly to enzymes. Tightly-bound cofactors are called prosthetic groups. Two explanations of how enzymes interact with substrates are the lock and key model, proposed by Emil Fischer in 1894, and the induced fit model, which is a modification of the lock and key model that was proposed by Daniel Koshland in 1958. In the lock and key model, the enzyme and the substrate have three-dimensional shapes that fit each other. The induced fit model proposes enzyme molecules can change their shape, depending on the interaction with the substrate. In this model, the enzyme and sometimes the substrate change shape as they interact until the active site is fully bound. Examples of Enzymes Over 5,000 biochemical reactions are known to be catalyzed by enzymes. The molecules are also used in industry and household products. Enzymes are used to brew beer and to make wine and cheese. Enzyme deficiencies are associated with some diseases, such as phenylketonuria and albinism. Here are a few examples of common enzymes: Amylase in saliva catalyzes the initial digestion of carbohydrates in food.Papain is a common enzyme found in meat tenderizer, where it acts to break the bonds holding protein molecules together.Enzymes are found in laundry detergent and stain removers to help break up protein stains and dissolve oils on fabrics.DNA polymerase catalyzes a reaction when DNA is being copied and then checks to make sure the correct bases are being used. Are All Enzymes Proteins? Nearly all known enzymes are proteins. At one time, it was believed all enzymes were proteins, but certain nucleic acids, called catalytic RNAs or ribozymes, have been discovered that have catalytic properties. Most of the time students study enzymes, they are really studying protein-based enzymes, since very little is known about how RNA can act as a catalyst.
Sunday, November 3, 2019
Yellow Rain Research Paper Example | Topics and Well Written Essays - 1250 words
Yellow Rain - Research Paper Example Therefore, the US government made a case stating that around tens of thousands of people was killed on account of yellow rain since it contained contagious chemicals harmful for human life. However, the accusations were denied by Soviet Union while the UN investigations also didn’t prove to be futile in this context. In addition, a few of the samples containing the chemical were tested by an independent group of scientists which in reality proved to be merely honeybee feces. This discovery suggested that the liquid came about after defecating digested pollen out of bees swarms. Yet, there are conflicting views regarding these claims and various scientists offer diverse opinions on the subject. USA, however, haven’t backed off from the allegations till date and thus the issue is still often touched upon at various instances. For these reasons, the paper will present a study on various aspects of the yellow rain including a historic perspective and various hypothesis pres ented over time to explain the underlying concepts of the chemical. The concept of yellow rain emerged back in 1975 when various events in Vietnam and Laos took place with alleged involvement of Soviet Union. Refugees have reported that various instances which took place during the insurgency movement in these states involved chemical warfare via low flying helicopters or aircrafts (Ferrel 2013). These refugees describe that an oily yellow liquid which was later popularized as yellow rain was seen dropping from these aircrafts which produced chronic symptoms. These symptoms were related to but not limited to neurological disorders, for instance, seizures, bleeding and sometimes even blindness. These ailments were similar to those reported in Vietnamese insurgency which has occurred in Cambodia. In this context, a textbook maybe quoted which was authored by the Army Medical Department of USA which
Friday, November 1, 2019
Language Issues in Public Discourse Research Paper - 1
Language Issues in Public Discourse - Research Paper Example This essay will explore three ways in which the English language is changing, and the discourse around those changes, as they are being debated and discussed in the media. Political language and how it changed during the Bush era in the United States is being discussed widely in academic circles and this phenomenon will be examined and analyzed briefly. The printed media particularly in Great Britain raises the question of American terms and their effect on English worldwide. Contemporary magazine and newspaper articles form the basis of the discussion of the British attitude to American language in this essay. Current discussions regarding spelling are examined, from the perspective of young people, citing as examples a web forum, and the transcript of a high school debate. Finally, the trend toward politically correct language is the focus, with spoken and institutionalized language being examined. In short, this essay will comment on the changing language and how these changes are perceived across a reasonably wide spectrum of English speakers. (Not included in word limit) The Essay When discourse is analyzed, the linguistic output of someone other than the analyst is examined (Brown & Yule, 1983: 2). This implies that the analyst also contributes his/her own meaning to the analysis, and that the context of more than just the words, and the grammar of the language are at play. Brown and Yule (1983: 3) further contend that the language may contain features such as â€Å"†¦ hesitations, slips and non-standard forms†so that an analysis of written text on its own is perhaps never altogether complete. It is, however, also true that â€Å" †¦ the task is this: to think more deeply about the meanings we give people’s words do as to make ourselves better, more humane people and the world a better, more humane place.†(Gee, 2005: 3). Hence it is necessary to examine many aspects of language if a fuller understanding of the meaning of s ocial worlds as all individuals experience them is to be reached. There are certain aspects of language that are clearly of some concern to analysts and general public commentators. Media, both print and electronic, carries a significant amount of comment on the changing nature of English. Sometimes these aspects are serious and of great importance in the formation of the societies and their attitudes, values and behaviors; sometimes they are less serious but still interesting from a social and psychological perspective. One area which does carry great weight is in the leadership of societies. The leaders of communities worldwide do use language to form meanings and the understanding of the public. Hence it is necessary that everyone remain aware of the possible hidden meaning and unrevealed intentions of leaders and particularly politicians. When politicians speak, it is widely accepted that their motives are not always directly connected to the words and language they are using. I nevitably, their language has characteristics that show the real intention of their words: to persuade the public that what they say is correct, and that they should be voted for in the next election. Elena Mihas of the University of Wisconsin-Milwaukee has examined and commented on the language used during the Bush era in the United States. She highlights specifically the metaphoric and euphemistic forms of language used by politicians in this period, in addition to examining the coherence, arguments,
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